Mediterranean Cruises Sailing from Southampton

Mediterranean Cruise

Mediterranean cruises sailing from Southampton offer one of the most convenient and relaxing ways to explore southern Europe without flying. With a wide choice of itineraries and cruise lines departing directly from the UK, you can set off on a sun-drenched adventure to Spain, France, Italy, Greece, and beyond – all from the comfort of your local port. Popular with both first-time and seasoned cruisers, these no-fly cruises combine ease and elegance, with durations ranging from 7 to over 21 nights. With Hello Cruise, you can compare dates, itineraries, cruise lines, and exclusive deals from trusted cruise agents.

Cruises to the Mediterranean from Southampton are available with leading cruise lines including P&O Cruises, Cunard, MSC Cruises, and Princess. Whether you’re dreaming of a relaxing beach break, cultural discoveries, or island hopping across the Aegean, there’s an itinerary to suit. These cruises often include scenic sea days before reaching key ports such as Barcelona, Rome (Civitavecchia), and Marseille. Many itineraries also combine western and eastern Mediterranean highlights into one seamless journey. For a truly hassle-free holiday, cruises from Southampton to the Mediterranean are a popular no-fly favourite.

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16nov2025

Queen Anne

Cunard Cruises Logo

Queen Anne’s breathtaking interiors take inspiration from our past to define a striking new design direction for our future. Come on board to discover a ship that is modern, yet timeless. A ship that offers both exciting, novel experiences, as well as our much-loved signature venues.On a Queen Anne voyage feel inspired by the blend of classic and contemporary. Enjoy the freedom to do as little or as much as you choose and indulge in everything that makes a Cunard ship so special. With luxurious flourishes enhanced by stylish décor, every day on Queen Anne offers a chance to sail the world in unparalleled comfort. Let tension dissipate in the tranquillity that awaits at the Mareel Spa, delight in the ceremony of our signature Afternoon Tea, and enjoy that extra special feeling as you descend into the Grand Lobby in your Gala Evening finery. Above all, rest easy in the knowledge that the finer details have been taken care of. We look forward to welcoming you on board.

  • Mega Ship
  • Timeless
  • Premium

Cruise: Southampton – Lisbon – Málaga – Tangier – Vigo – Southampton

10 nights

04dec2025

Queen Victoria

Cunard Cruises Logo

Queen Victoria will delight you with her special appeal, where elegance and unique features combine seamlessly with outstanding hospitality. You’ll discover an extraordinary way to see the world.From the moment you step on board, you’re immersed in an enchanting world of pleasure and escapism. Pass leisurely days soaking up the sunshine or gazing out at the tranquil ocean from her light-filled Winter Garden. Learn something new with our Cunard Insights speakers, or simply unwind with a good read. As evening falls, choose from a delectable array of dining options, and enjoy world-class entertainment in the Royal Court Theatre. On Queen Victoria the freedom to create your perfect trip is all yours.

  • Mega Ship
  • Timeless
  • Premium

Cruise: Southampton – Cádiz – Málaga – Barcelona – Alicante – Lisbon – Southampton

12 nights

21feb2026

Iona

P&O Cruises Logo

Innovation meets explorationYou’ve not cruised until you’ve sailed on Iona, with her cutting-edge design and world-class style. Explore the world in widescreen with the dazzling SkyDome, swim with panoramic views, and indulge in a world of dining and extraordinary entertainment. Get ready for the adventure of a lifetime on Iona.

  • Mid-Size Ship
  • British
  • Family-Friendly

Cruise: Southampton – Vigo – La Coruña – Getxo – Cherbourg – Southampton

23mar2026

Sky Princess

Princess Cruises Logo

Taking sea travel to new heightsSky Princess® elevates the distinctive, contemporary design and luxurious attractions of our renowned Royal-class ships to even loftier heights. You can look forward to our most exciting entertainment venues yet, our newest dining choices and award-winning chef partnerships, as well as more staterooms than ever to relax in. And that’s just the start.

  • Mid-Size Ship
  • Great Value
  • Premium

Cruise: Southampton – La Coruña – Bilbao – Le Verdon-sur-Mer – Cherbourg – Southampton

04apr2026

Queen Victoria

Cunard Cruises Logo

Queen Victoria will delight you with her special appeal, where elegance and unique features combine seamlessly with outstanding hospitality. You’ll discover an extraordinary way to see the world.From the moment you step on board, you’re immersed in an enchanting world of pleasure and escapism. Pass leisurely days soaking up the sunshine or gazing out at the tranquil ocean from her light-filled Winter Garden. Learn something new with our Cunard Insights speakers, or simply unwind with a good read. As evening falls, choose from a delectable array of dining options, and enjoy world-class entertainment in the Royal Court Theatre. On Queen Victoria the freedom to create your perfect trip is all yours.

  • Mega Ship
  • Timeless
  • Premium

Cruise: Southampton – Leixões – La Coruña – Gijón – Pauillac – Southampton

08apr2026

Ventura

P&O Cruises Logo

The fun all-rounderDiscover the perfect blend of fun, relaxation, and style on Ventura. Designed for guests of all ages, this lively ship invites you to unwind at The Retreat, get creative with hands-on workshops, and enjoy thrilling live shows at the Arena Theatre. With restaurants and bars to please every palate and endless entertainment to keep the kids happy, Ventura offers unforgettable experiences for everyone.There’s always something happening on Ventura, enjoy delicious fine dining, a tranquil spa, many quiet spaces to unwind, great sports facilities and four pools. Evenings are particularly memorable, with the lavish two-deck theatre where you’ll witness elaborate shows and stand-up comedy.

  • Large Ship
  • British
  • Family-Friendly

Cruise: Southampton – Santander – Lisbon – Lisbon – Leixões – Vigo – Cherbourg – Southampton

10 nights

11apr2026

Sky Princess

Princess Cruises Logo

Taking sea travel to new heightsSky Princess® elevates the distinctive, contemporary design and luxurious attractions of our renowned Royal-class ships to even loftier heights. You can look forward to our most exciting entertainment venues yet, our newest dining choices and award-winning chef partnerships, as well as more staterooms than ever to relax in. And that’s just the start.

  • Mid-Size Ship
  • Great Value
  • Premium

Cruise: Southampton – Cádiz – Barcelona – La Seyne-sur-Mer – Livorno – Civitavecchia – Alghero – Southampton

12apr2026

Arvia

P&O Cruises Logo

Arvia is all about luxury. Swim-up bars, infinity pools and the retractable SkyDome. Take some time out in The Retreat, a private deck where you can relax in style. If you’re looking for excitement, Keel and Cow offers a gastropub experience out on the high seas, while The Club House becomes the party centre of the ship at night.

  • Mid-Size Ship
  • British
  • Family-Friendly

Cruise: Southampton – Cádiz – Barcelona – La Seyne-sur-Mer – La Spezia – Civitavecchia – Alicante – Southampton

14 nights

24apr2026

Queen Victoria

Cunard Cruises Logo

Queen Victoria will delight you with her special appeal, where elegance and unique features combine seamlessly with outstanding hospitality. You’ll discover an extraordinary way to see the world.From the moment you step on board, you’re immersed in an enchanting world of pleasure and escapism. Pass leisurely days soaking up the sunshine or gazing out at the tranquil ocean from her light-filled Winter Garden. Learn something new with our Cunard Insights speakers, or simply unwind with a good read. As evening falls, choose from a delectable array of dining options, and enjoy world-class entertainment in the Royal Court Theatre. On Queen Victoria the freedom to create your perfect trip is all yours.

  • Mega Ship
  • Timeless
  • Premium

Cruise: Southampton – La Coruña – Lisbon – Málaga – Cartagena – Palma de Mallorca – Barcelona

24apr2026

Queen Victoria

Cunard Cruises Logo

Queen Victoria will delight you with her special appeal, where elegance and unique features combine seamlessly with outstanding hospitality. You’ll discover an extraordinary way to see the world.From the moment you step on board, you’re immersed in an enchanting world of pleasure and escapism. Pass leisurely days soaking up the sunshine or gazing out at the tranquil ocean from her light-filled Winter Garden. Learn something new with our Cunard Insights speakers, or simply unwind with a good read. As evening falls, choose from a delectable array of dining options, and enjoy world-class entertainment in the Royal Court Theatre. On Queen Victoria the freedom to create your perfect trip is all yours.

  • Mega Ship
  • Timeless
  • Premium

Cruise: Southampton – La Coruña – Lisbon – Málaga – Cartagena – Palma de Mallorca – Barcelona – Heraklion (Iraklion), Crete – Kusadasi – Dardanelles – Istanbul – Istanbul

24apr2026

Queen Victoria

Cunard Cruises Logo

Queen Victoria will delight you with her special appeal, where elegance and unique features combine seamlessly with outstanding hospitality. You’ll discover an extraordinary way to see the world.From the moment you step on board, you’re immersed in an enchanting world of pleasure and escapism. Pass leisurely days soaking up the sunshine or gazing out at the tranquil ocean from her light-filled Winter Garden. Learn something new with our Cunard Insights speakers, or simply unwind with a good read. As evening falls, choose from a delectable array of dining options, and enjoy world-class entertainment in the Royal Court Theatre. On Queen Victoria the freedom to create your perfect trip is all yours.

  • Mega Ship
  • Timeless
  • Premium

Cruise: Southampton – La Coruña – Lisbon – Málaga – Cartagena – Palma de Mallorca – Barcelona – Heraklion (Iraklion), Crete – Kusadasi – Dardanelles – Istanbul – Istanbul – Dardanelles – Piraeus – Mykonos – Katakolon – Messina Strait – Barcelona

24apr2026

Aurora

P&O Cruises Logo

Experience the timeless elegance of Aurora. This adults-only ship exudes classic cruising with a modern twist; with its stunning atrium and refined design, you can indulge in relaxing afternoons, explore destinations, and appreciate the art of leisurely cruising. From relaxing on the sun-drenched Lido deck to enjoying British afternoon tea or exploring extraordinary itineraries, unforgettable adventures await on Aurora.

  • Large Ship
  • British
  • Adults Only

Cruise: Southampton – Cartagena – Cagliari – Katakolon – Corfu – Dubrovnik – Split – Catania – Gibraltar – Southampton

24apr2026

Queen Victoria

Cunard Cruises Logo

Queen Victoria will delight you with her special appeal, where elegance and unique features combine seamlessly with outstanding hospitality. You’ll discover an extraordinary way to see the world.From the moment you step on board, you’re immersed in an enchanting world of pleasure and escapism. Pass leisurely days soaking up the sunshine or gazing out at the tranquil ocean from her light-filled Winter Garden. Learn something new with our Cunard Insights speakers, or simply unwind with a good read. As evening falls, choose from a delectable array of dining options, and enjoy world-class entertainment in the Royal Court Theatre. On Queen Victoria the freedom to create your perfect trip is all yours.

  • Mega Ship
  • Timeless
  • Premium

Cruise: Southampton – La Coruña – Lisbon – Málaga – Cartagena – Palma de Mallorca – Barcelona – Heraklion (Iraklion), Crete – Kusadasi – Dardanelles – Istanbul – Istanbul – Dardanelles – Piraeus – Mykonos – Katakolon – Messina Strait – Barcelona – La Seyne-sur-Mer – Livorno – Ibiza – Valencia – Barcelona

25apr2026

Iona

P&O Cruises Logo

Innovation meets explorationYou’ve not cruised until you’ve sailed on Iona, with her cutting-edge design and world-class style. Explore the world in widescreen with the dazzling SkyDome, swim with panoramic views, and indulge in a world of dining and extraordinary entertainment. Get ready for the adventure of a lifetime on Iona.

  • Mid-Size Ship
  • British
  • Family-Friendly

Cruise: Southampton – Getxo – La Coruña – Vigo – Cherbourg – Southampton

26apr2026

Arvia

P&O Cruises Logo

Arvia is all about luxury. Swim-up bars, infinity pools and the retractable SkyDome. Take some time out in The Retreat, a private deck where you can relax in style. If you’re looking for excitement, Keel and Cow offers a gastropub experience out on the high seas, while The Club House becomes the party centre of the ship at night.

  • Mid-Size Ship
  • British
  • Family-Friendly

Cruise: Southampton – Gibraltar – Málaga – Alicante – La Seyne-sur-Mer – Barcelona – Cádiz – Southampton

05may2026

Borealis

Fred.Olsen Cruises Logo

Sister ship of our flagship Bolette, Borealis joined us 2020, and is perfectly suited for enjoying scenic cruising of the world’s lesser-known waterways. From cruising past remarkable landscapes and historical sites to capturing the beauty of the natural world. Redecorated and refurbished when she joined our fleet in order to meet the high standards of the Olsen family, Borealis features a wonderful series of lounges, bars, elegant restaurants and wide-open deck spaces, as well as 702 beautiful cabins and suites; perfectly suited to the Fred. Olsen style of cruising. From January 2026, Borealis will be excusively for adults, so you can relax in the company of other like-minded guests.Enjoy Scenic Discoveries from the perfectly-appointed Observatory, where guests will be able to see outstanding natural scenery and iconic landmarks, accompanied by commentary from our on board teams; or sample delicious Treats of the Region in the Auditorium where our talented chefs will prepare dishes that are local to the exciting destinations you’re visiting. Our friendly crew will be on hand throughout your cruise, providing the personal service they’re known for. 

  • Mid-Size Ship
  • Over 55s+
  • Adults Only
  • Traditional

Cruise: Southampton – Gibraltar – Palamós – Savona – Genoa – Genoa – Portofino – Livorno – La Spezia – Cartagena – Southampton

10may2026

Arvia

P&O Cruises Logo

Arvia is all about luxury. Swim-up bars, infinity pools and the retractable SkyDome. Take some time out in The Retreat, a private deck where you can relax in style. If you’re looking for excitement, Keel and Cow offers a gastropub experience out on the high seas, while The Club House becomes the party centre of the ship at night.

  • Mid-Size Ship
  • British
  • Family-Friendly

Cruise: Southampton – Cádiz – Barcelona – La Seyne-sur-Mer – La Spezia – Civitavecchia – Alicante – Southampton

11may2026

Queen Anne

Cunard Cruises Logo

Queen Anne’s breathtaking interiors take inspiration from our past to define a striking new design direction for our future. Come on board to discover a ship that is modern, yet timeless. A ship that offers both exciting, novel experiences, as well as our much-loved signature venues.On a Queen Anne voyage feel inspired by the blend of classic and contemporary. Enjoy the freedom to do as little or as much as you choose and indulge in everything that makes a Cunard ship so special. With luxurious flourishes enhanced by stylish décor, every day on Queen Anne offers a chance to sail the world in unparalleled comfort. Let tension dissipate in the tranquillity that awaits at the Mareel Spa, delight in the ceremony of our signature Afternoon Tea, and enjoy that extra special feeling as you descend into the Grand Lobby in your Gala Evening finery. Above all, rest easy in the knowledge that the finer details have been taken care of. We look forward to welcoming you on board.

  • Mega Ship
  • Timeless
  • Premium

Cruise: Southampton – Cartagena – Messina Strait – Corfu – Dubrovnik – Zadar – Messina Strait – Cagliari – Málaga – Gibraltar – Southampton

13may2026

Aurora

P&O Cruises Logo

Experience the timeless elegance of Aurora. This adults-only ship exudes classic cruising with a modern twist; with its stunning atrium and refined design, you can indulge in relaxing afternoons, explore destinations, and appreciate the art of leisurely cruising. From relaxing on the sun-drenched Lido deck to enjoying British afternoon tea or exploring extraordinary itineraries, unforgettable adventures await on Aurora.

  • Large Ship
  • British
  • Adults Only

Cruise: Southampton – La Coruña – Leixões – Tangier – Valletta – Messina – Salerno – Civitavecchia – Ajaccio, Corsica – Alicante – Lisbon – Southampton

23may2026

Ventura

P&O Cruises Logo

The fun all-rounderDiscover the perfect blend of fun, relaxation, and style on Ventura. Designed for guests of all ages, this lively ship invites you to unwind at The Retreat, get creative with hands-on workshops, and enjoy thrilling live shows at the Arena Theatre. With restaurants and bars to please every palate and endless entertainment to keep the kids happy, Ventura offers unforgettable experiences for everyone.There’s always something happening on Ventura, enjoy delicious fine dining, a tranquil spa, many quiet spaces to unwind, great sports facilities and four pools. Evenings are particularly memorable, with the lavish two-deck theatre where you’ll witness elaborate shows and stand-up comedy.

  • Large Ship
  • British
  • Family-Friendly

Cruise: Southampton – La Coruña – Gijón – Santander – La Rochelle – Southampton

24may2026

Arvia

P&O Cruises Logo

Arvia is all about luxury. Swim-up bars, infinity pools and the retractable SkyDome. Take some time out in The Retreat, a private deck where you can relax in style. If you’re looking for excitement, Keel and Cow offers a gastropub experience out on the high seas, while The Club House becomes the party centre of the ship at night.

  • Mid-Size Ship
  • British
  • Family-Friendly

Cruise: Southampton – Getxo – La Coruña – Vigo – Cherbourg – Southampton

30may2026

Iona

P&O Cruises Logo

Innovation meets explorationYou’ve not cruised until you’ve sailed on Iona, with her cutting-edge design and world-class style. Explore the world in widescreen with the dazzling SkyDome, swim with panoramic views, and indulge in a world of dining and extraordinary entertainment. Get ready for the adventure of a lifetime on Iona.

  • Mid-Size Ship
  • British
  • Family-Friendly

Cruise: Southampton – Getxo – La Coruña – Vigo – Cherbourg – Southampton

31may2026

Liberty of the Seas

Royal Caribbean Logo

From Summer 2026, go even bolder in Europe on the newly Amplified Liberty of the Seas® after a makeover for the ages, bringing all-new adventures to a fleet favourite ship. Dial thrills all the way up, conquering a new Royal Escape Room and twisting, turning dares on The Perfect Storm waterslides — including the first boomerang slide at sea. Charge up your chill with private new casitas complete with attendant service and cocktails from The Lime and Coconut® at the totally-revamped pool deck. Fill up on fresh faves at 15 crave- worthy restaurants like the new El Loco Fresh® and Izumi Teppanyaki. And hit a bolder jackpot at the expanded casino, loaded with even more slots and table games. Take your holiday to the next level on the newly Amplified Liberty of the Seas®, sailing from Southampton summer 2026.

  • Large Ship
  • Fun-filled
  • Family-Friendly

Cruise: Southampton – Vigo – Lisbon – Bilbao – Southampton

31may2026

Arvia

P&O Cruises Logo

Arvia is all about luxury. Swim-up bars, infinity pools and the retractable SkyDome. Take some time out in The Retreat, a private deck where you can relax in style. If you’re looking for excitement, Keel and Cow offers a gastropub experience out on the high seas, while The Club House becomes the party centre of the ship at night.

  • Mid-Size Ship
  • British
  • Family-Friendly

Cruise: Southampton – Getxo – La Coruña – Vigo – Cherbourg – Southampton

05jun2026

Britannia

P&O Cruises Logo

Contemporary glamourExplore the world in understated luxury on our stylish, family-friendly flagship, Britannia. Elegant interiors create a boutique hotel ambience at sea, while her stunning three- tier atrium, adorned with a Star Burst sculpture, provides that wow-factor entrance. Whether you want to relax and unwind, indulge yourself or be entertained, you can do it in style on board Britannia.

  • Mid-Size Ship
  • British
  • Family-Friendly

Cruise: Southampton – Cartagena – Cagliari – Corfu – Corfu – Zadar – Split – Valletta – Palma de Mallorca – La Coruña – Southampton