Mediterranean Cruises from Rome

Set sail on unforgettable Mediterranean cruises from Rome in 2025, 2026 or even looking ahead to 2027. As one of the most iconic departure ports in Europe, Rome (via Civitavecchia) offers incredible access to Western and Eastern Mediterranean itineraries. From exploring the French Riviera and the Greek Islands to calling at historic ports in Turkey, Croatia, and Spain – cruises from Rome are ideal for travellers seeking cultural depth and sun-soaked coastlines. With Hello Cruise, you can compare cruise lines, dates, and itineraries – plus browse prices and offers from leading cruise agents, including cruise and stay options in Rome for more time to explore this magnificent city.
747 cruises
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
The second stunning ship in the Prima Class, Norwegian Viva® is designed for you to live life to the fullest. Stretch out, way out, in some of our most spacious accommodations. Stay connected to the ocean along the 360° Ocean Boulevard or by enjoying a dip in the Infinity pool. And with high staff-to-guest levels, you’ll always feel prioritized and pampered. From our three-story race track and immersive virtual-reality games to the luxurious Mandara Spa® and mesmerising three-story theatre that transforms into a Vegas-style nightclub, get ready to live it up on Norwegian Viva from sunrise to long after the sun has set.
- Mega Ship
- Relaxed
- Family-Friendly
Cruise: Civitavecchia – Naples – Livorno – Marseille – Barcelona – Palma de Mallorca – Ibiza – Cartagena – Málaga – Cádiz – Lisbon
10 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
MSC Magnifica is thoughtfully designed for longer voyages, offering almost exclusively balcony cabins and exceptionally generous indoor and outdoor spaces. Guests can enjoy a range of water facilities, including an indoor pool ideal for all-weather relaxation, as well as dedicated kids’ areas, restaurants where personalised service enhance every dining experience, along with a theatre presenting a spectacular show every evening.Masterfully combining variety with luxury, MSC Magnifica is introducing a brand-new MSC Yacht Club, launching in Summer 2026. This exceptional remodelling opens the way for an elevated and exclusive onboard experience where privacy meets exclusivity, where every detail is crafted to exceed your highest expectations.This is a captivating new chapter in the story of a much-loved ship: a brand-new MSC Yacht Club, an upgraded wellness offering with a new MSC Aurea Spa and a reimagined gym.MSC Magnifica lives up to her name – she offers a cruise that’s memorably magnificent.
- Mega Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Genoa – Marseille – Genoa – Marseille – Barcelona
5 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
MSC Magnifica is thoughtfully designed for longer voyages, offering almost exclusively balcony cabins and exceptionally generous indoor and outdoor spaces. Guests can enjoy a range of water facilities, including an indoor pool ideal for all-weather relaxation, as well as dedicated kids’ areas, restaurants where personalised service enhance every dining experience, along with a theatre presenting a spectacular show every evening.Masterfully combining variety with luxury, MSC Magnifica is introducing a brand-new MSC Yacht Club, launching in Summer 2026. This exceptional remodelling opens the way for an elevated and exclusive onboard experience where privacy meets exclusivity, where every detail is crafted to exceed your highest expectations.This is a captivating new chapter in the story of a much-loved ship: a brand-new MSC Yacht Club, an upgraded wellness offering with a new MSC Aurea Spa and a reimagined gym.MSC Magnifica lives up to her name – she offers a cruise that’s memorably magnificent.
- Mega Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Genoa – Marseille – Alicante – Valencia – Barcelona – Civitavecchia
8 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
MSC Magnifica is thoughtfully designed for longer voyages, offering almost exclusively balcony cabins and exceptionally generous indoor and outdoor spaces. Guests can enjoy a range of water facilities, including an indoor pool ideal for all-weather relaxation, as well as dedicated kids’ areas, restaurants where personalised service enhance every dining experience, along with a theatre presenting a spectacular show every evening.Masterfully combining variety with luxury, MSC Magnifica is introducing a brand-new MSC Yacht Club, launching in Summer 2026. This exceptional remodelling opens the way for an elevated and exclusive onboard experience where privacy meets exclusivity, where every detail is crafted to exceed your highest expectations.This is a captivating new chapter in the story of a much-loved ship: a brand-new MSC Yacht Club, an upgraded wellness offering with a new MSC Aurea Spa and a reimagined gym.MSC Magnifica lives up to her name – she offers a cruise that’s memorably magnificent.
- Mega Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Genoa – Marseille – Alicante – Valencia – Barcelona – Civitavecchia
8 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
Silver Muse is our inspirational work of art. With her eight dining venues, spacious outdoor areas, and up-to-the-minute technology, she’s the best place between sea and sky.Silver Muse marked a new era of ultra-luxury ocean travel for us—enhancing the small-ship intimacy and spacious all-suite accommodation that are our hallmarks but raising the bar in terms of luxury. Silver Muse offers a wealth of enhancements to the onboard experience while satisfying our uncompromising requirements for comfort, service, dining, and quality for the world’s most discerning travellers.Silver Muse pioneered the balance between small-ship intimacy and spacious all-suite accommodation. One of the larger ships in our fleet, she offers eight dining offers, plenty of onboard entertainment, and a wide choice of public areas. She’s simply divine!
- Small Ship
Cruise: Civitavecchia – Naples – Palermo – Valletta – Valletta – La Goulette – Cagliari – Valencia – Barcelona
10 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
Silver Muse is our inspirational work of art. With her eight dining venues, spacious outdoor areas, and up-to-the-minute technology, she’s the best place between sea and sky.Silver Muse marked a new era of ultra-luxury ocean travel for us—enhancing the small-ship intimacy and spacious all-suite accommodation that are our hallmarks but raising the bar in terms of luxury. Silver Muse offers a wealth of enhancements to the onboard experience while satisfying our uncompromising requirements for comfort, service, dining, and quality for the world’s most discerning travellers.Silver Muse pioneered the balance between small-ship intimacy and spacious all-suite accommodation. One of the larger ships in our fleet, she offers eight dining offers, plenty of onboard entertainment, and a wide choice of public areas. She’s simply divine!
- Small Ship
Cruise: Civitavecchia – Livorno – Livorno – Genoa – Genoa – Naples – Naples – Split – Zadar – Fusina
10 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
Silver Muse is our inspirational work of art. With her eight dining venues, spacious outdoor areas, and up-to-the-minute technology, she’s the best place between sea and sky.Silver Muse marked a new era of ultra-luxury ocean travel for us—enhancing the small-ship intimacy and spacious all-suite accommodation that are our hallmarks but raising the bar in terms of luxury. Silver Muse offers a wealth of enhancements to the onboard experience while satisfying our uncompromising requirements for comfort, service, dining, and quality for the world’s most discerning travellers.Silver Muse pioneered the balance between small-ship intimacy and spacious all-suite accommodation. One of the larger ships in our fleet, she offers eight dining offers, plenty of onboard entertainment, and a wide choice of public areas. She’s simply divine!
- Small Ship
Cruise: Civitavecchia – Naples – Menton – Menton – Genoa – Villefranche-sur-Mer – Villefranche-sur-Mer – Valencia – Palma de Mallorca – Palamós – Barcelona
10 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.
- Mid-Size Ship
- Fun
- Family-Friendly
Cruise: Civitavecchia – Messina – Valletta – Barcelona – Marseille – Genoa – Civitavecchia
7 nights
From sumptuous dining to captivating diversions, discover the many riches of this gemAs you set your sights on the wonders of the world, let Sapphire Princess indulge your every whim. Over 700 balconies, world-class gourmet dining and dazzling entertainment options are just the beginning of your sea-going adventure. Dance the night away, enjoy casino gaming or relax and rejuvenate body and mind at the Lotus Spa®.
- Mega Ship
- Great Value
- Premium
Cruise: Civitavecchia – Corfu – Dubrovnik – Kotor – Naples – Civitavecchia
7 nights
From sumptuous dining to captivating diversions, discover the many riches of this gemAs you set your sights on the wonders of the world, let Sapphire Princess indulge your every whim. Over 700 balconies, world-class gourmet dining and dazzling entertainment options are just the beginning of your sea-going adventure. Dance the night away, enjoy casino gaming or relax and rejuvenate body and mind at the Lotus Spa®.
- Mega Ship
- Great Value
- Premium
Cruise: Civitavecchia – Corfu – Dubrovnik – Kotor – Naples – Civitavecchia – Sarandë – Katakolon – Valletta – Catania – Naples – Civitavecchia
14 nights