Mediterranean Cruises from Malta

Mediterranean Cruise

Mediterranean cruises from Malta are ideal for travellers looking to explore the region from the heart of the Med. Departures from Valletta in 2025, 2026, and 2027 are available with a variety of cruise lines, including MSC Cruises, P&O Cruises and Silversea. Itineraries typically cover Greece, Italy, Spain, and France, with both roundtrip and one-way options. Malta’s strategic location allows for immersive cultural cruises or relaxing island-hopping getaways. With Hello Cruise, you can compare itineraries, cruise lines, sailing dates, cruise and stay packages and prices from trusted UK cruise agents – all in one place.

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02apr2026

Azura

P&O Cruises Logo

A social paradise at seaWhether you seek family fun, romantic moments, or a personal retreat, Azura offers the perfect blend of entertainment and relaxation. Between visiting sun-soaked destinations, why not unwind by the pool, enjoy dazzling shows at The Playhouse, indulge in alfresco treatments at The Retreat, and experience unforgettable dining at venues like The Glass House? With so many venues, there’s something for everyone onboard Azura.

  • Mega Ship
  • British
  • Family-Friendly

Cruise: Valletta – La Seyne-sur-Mer – Livorno – Civitavecchia – Naples – Valletta

02apr2026

Azura

P&O Cruises Logo

A social paradise at seaWhether you seek family fun, romantic moments, or a personal retreat, Azura offers the perfect blend of entertainment and relaxation. Between visiting sun-soaked destinations, why not unwind by the pool, enjoy dazzling shows at The Playhouse, indulge in alfresco treatments at The Retreat, and experience unforgettable dining at venues like The Glass House? With so many venues, there’s something for everyone onboard Azura.

  • Mega Ship
  • British
  • Family-Friendly

Cruise: Valletta – La Seyne-sur-Mer – Livorno – Civitavecchia – Naples – Valletta – Valletta – Split – Zadar – Dubrovnik – Valletta

02apr2026

Silver Shadow

Silversea Cruises Logo

Award-winning Silver Shadow is a firm favorite in the Silversea fleet. With one of the highest space-to-guest ratios at sea, she offers authentic experiences, simple pleasures, and shared moments.Silversea’s Shadow Class luxury cruise ships Silver Shadow and Silver Whisper offer you freedom and space to design your day. Silver Shadow retains Silversea’s essence—spacious suites and superior service—paired with a lively cosmopolitan atmosphere and enhanced amenities. Energise body and mind in the upgraded spa and fitness centre. Savour fine wines and French gastronomy in La Dame and enjoy authentic Italian cuisine in La Terrazza, endless ocean views from The Grill, and internationally inspired dishes in The Restaurant. From delectable dining to relaxation in ultra luxury, cruising has never felt so good.

  • Small Ship

Cruise: Valletta – Taormina – Salerno – Ponza Island – Portoferraio – Portofino – Nice

09apr2026

Azura

P&O Cruises Logo

A social paradise at seaWhether you seek family fun, romantic moments, or a personal retreat, Azura offers the perfect blend of entertainment and relaxation. Between visiting sun-soaked destinations, why not unwind by the pool, enjoy dazzling shows at The Playhouse, indulge in alfresco treatments at The Retreat, and experience unforgettable dining at venues like The Glass House? With so many venues, there’s something for everyone onboard Azura.

  • Mega Ship
  • British
  • Family-Friendly

Cruise: Valletta – Valletta – Split – Zadar – Dubrovnik – Valletta

09apr2026

Azura

P&O Cruises Logo

A social paradise at seaWhether you seek family fun, romantic moments, or a personal retreat, Azura offers the perfect blend of entertainment and relaxation. Between visiting sun-soaked destinations, why not unwind by the pool, enjoy dazzling shows at The Playhouse, indulge in alfresco treatments at The Retreat, and experience unforgettable dining at venues like The Glass House? With so many venues, there’s something for everyone onboard Azura.

  • Mega Ship
  • British
  • Family-Friendly

Cruise: Valletta – Valletta – Split – Zadar – Dubrovnik – Valletta – Valletta – Piraeus – Suda Bay, Crete – Katakolon – Valletta

16apr2026

Azura

P&O Cruises Logo

A social paradise at seaWhether you seek family fun, romantic moments, or a personal retreat, Azura offers the perfect blend of entertainment and relaxation. Between visiting sun-soaked destinations, why not unwind by the pool, enjoy dazzling shows at The Playhouse, indulge in alfresco treatments at The Retreat, and experience unforgettable dining at venues like The Glass House? With so many venues, there’s something for everyone onboard Azura.

  • Mega Ship
  • British
  • Family-Friendly

Cruise: Valletta – Valletta – Piraeus – Suda Bay, Crete – Katakolon – Valletta

16apr2026

Azura

P&O Cruises Logo

A social paradise at seaWhether you seek family fun, romantic moments, or a personal retreat, Azura offers the perfect blend of entertainment and relaxation. Between visiting sun-soaked destinations, why not unwind by the pool, enjoy dazzling shows at The Playhouse, indulge in alfresco treatments at The Retreat, and experience unforgettable dining at venues like The Glass House? With so many venues, there’s something for everyone onboard Azura.

  • Mega Ship
  • British
  • Family-Friendly

Cruise: Valletta – Valletta – Piraeus – Suda Bay, Crete – Katakolon – Valletta – Valletta – La Seyne-sur-Mer – La Spezia – Civitavecchia – Valletta

22apr2026

MSC World Europa

MSC Cruises Logo

Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.

  • Mid-Size Ship
  • Fun
  • Family-Friendly

Cruise: Valletta – Barcelona – Marseille – Genoa – Naples – Messina – Valletta

23apr2026

Azura

P&O Cruises Logo

A social paradise at seaWhether you seek family fun, romantic moments, or a personal retreat, Azura offers the perfect blend of entertainment and relaxation. Between visiting sun-soaked destinations, why not unwind by the pool, enjoy dazzling shows at The Playhouse, indulge in alfresco treatments at The Retreat, and experience unforgettable dining at venues like The Glass House? With so many venues, there’s something for everyone onboard Azura.

  • Mega Ship
  • British
  • Family-Friendly

Cruise: Valletta – Valletta – La Seyne-sur-Mer – La Spezia – Civitavecchia – Valletta

23apr2026

Azura

P&O Cruises Logo

A social paradise at seaWhether you seek family fun, romantic moments, or a personal retreat, Azura offers the perfect blend of entertainment and relaxation. Between visiting sun-soaked destinations, why not unwind by the pool, enjoy dazzling shows at The Playhouse, indulge in alfresco treatments at The Retreat, and experience unforgettable dining at venues like The Glass House? With so many venues, there’s something for everyone onboard Azura.

  • Mega Ship
  • British
  • Family-Friendly

Cruise: Valletta – Valletta – La Seyne-sur-Mer – La Spezia – Civitavecchia – Valletta – Corfu – Dubrovnik – Zadar – Kotor – Valletta

29apr2026

MSC World Europa

MSC Cruises Logo

Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.

  • Mid-Size Ship
  • Fun
  • Family-Friendly

Cruise: Valletta – Barcelona – Marseille – Genoa – Naples – Messina – Valletta

30apr2026

MSC Splendida

MSC Cruises Logo

Spectacular daysMSC Splendida carries you in comfort, style and luxury to the most desirable cruise destinations in the world, while at the same time being a beautiful destination in her own right. With so much to see and do on board, every day on MSC Splendida promises travellers of all ages a world of new discoveries, before they even step ashore.

  • Mid-Size Ship
  • Fun
  • Family-Friendly

Cruise: Valletta – Barcelona – Palma de Mallorca – Marseille – Livorno – Cagliari – Palermo – Valletta

30apr2026

Azura

P&O Cruises Logo

A social paradise at seaWhether you seek family fun, romantic moments, or a personal retreat, Azura offers the perfect blend of entertainment and relaxation. Between visiting sun-soaked destinations, why not unwind by the pool, enjoy dazzling shows at The Playhouse, indulge in alfresco treatments at The Retreat, and experience unforgettable dining at venues like The Glass House? With so many venues, there’s something for everyone onboard Azura.

  • Mega Ship
  • British
  • Family-Friendly

Cruise: Valletta – Corfu – Dubrovnik – Zadar – Kotor – Valletta

30apr2026

Azura

P&O Cruises Logo

A social paradise at seaWhether you seek family fun, romantic moments, or a personal retreat, Azura offers the perfect blend of entertainment and relaxation. Between visiting sun-soaked destinations, why not unwind by the pool, enjoy dazzling shows at The Playhouse, indulge in alfresco treatments at The Retreat, and experience unforgettable dining at venues like The Glass House? With so many venues, there’s something for everyone onboard Azura.

  • Mega Ship
  • British
  • Family-Friendly

Cruise: Valletta – Corfu – Dubrovnik – Zadar – Kotor – Valletta – Heraklion (Iraklion), Crete – Rhodes – Kusadasi – Piraeus – Valletta

06may2026

MSC World Europa

MSC Cruises Logo

Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.

  • Mid-Size Ship
  • Fun
  • Family-Friendly

Cruise: Valletta – Barcelona – Marseille – Genoa – Naples – Messina – Valletta

07may2026

Azura

P&O Cruises Logo

A social paradise at seaWhether you seek family fun, romantic moments, or a personal retreat, Azura offers the perfect blend of entertainment and relaxation. Between visiting sun-soaked destinations, why not unwind by the pool, enjoy dazzling shows at The Playhouse, indulge in alfresco treatments at The Retreat, and experience unforgettable dining at venues like The Glass House? With so many venues, there’s something for everyone onboard Azura.

  • Mega Ship
  • British
  • Family-Friendly

Cruise: Valletta – Heraklion (Iraklion), Crete – Rhodes – Kusadasi – Piraeus – Valletta

07may2026

Azura

P&O Cruises Logo

A social paradise at seaWhether you seek family fun, romantic moments, or a personal retreat, Azura offers the perfect blend of entertainment and relaxation. Between visiting sun-soaked destinations, why not unwind by the pool, enjoy dazzling shows at The Playhouse, indulge in alfresco treatments at The Retreat, and experience unforgettable dining at venues like The Glass House? With so many venues, there’s something for everyone onboard Azura.

  • Mega Ship
  • British
  • Family-Friendly

Cruise: Valletta – Heraklion (Iraklion), Crete – Rhodes – Kusadasi – Piraeus – Valletta – Korčula – Zadar – Trieste – Split – Valletta

08may2026

Silver Shadow

Silversea Cruises Logo

Award-winning Silver Shadow is a firm favorite in the Silversea fleet. With one of the highest space-to-guest ratios at sea, she offers authentic experiences, simple pleasures, and shared moments.Silversea’s Shadow Class luxury cruise ships Silver Shadow and Silver Whisper offer you freedom and space to design your day. Silver Shadow retains Silversea’s essence—spacious suites and superior service—paired with a lively cosmopolitan atmosphere and enhanced amenities. Energise body and mind in the upgraded spa and fitness centre. Savour fine wines and French gastronomy in La Dame and enjoy authentic Italian cuisine in La Terrazza, endless ocean views from The Grill, and internationally inspired dishes in The Restaurant. From delectable dining to relaxation in ultra luxury, cruising has never felt so good.

  • Small Ship

Cruise: Valletta – Taormina – Salerno – Ponza Island – Portoferraio – Portofino – Nice

13may2026

MSC World Europa

MSC Cruises Logo

Welcome to The Future of CruisingImagine the future of cruising and discover it in the revolutionary MSC World Class fleet.Entering service in 2022, MSC World Europa was the first ship in this trailblazing new generation.With their futuristic silhouette, signature plumb bow and Y-shaped aft, the ships in the MSC World class will looks like nothing else at sea, cutting through the water with ease and grace.To complete this revolution, we have also developed an immersive guest experience, so on MSC World Europa, guests can look forward to a holiday like no other.It’s a new class of emotions, for the future of cruising.

  • Mid-Size Ship
  • Fun
  • Family-Friendly

Cruise: Valletta – Barcelona – Marseille – Genoa – Naples – Messina – Valletta

14may2026

Azura

P&O Cruises Logo

A social paradise at seaWhether you seek family fun, romantic moments, or a personal retreat, Azura offers the perfect blend of entertainment and relaxation. Between visiting sun-soaked destinations, why not unwind by the pool, enjoy dazzling shows at The Playhouse, indulge in alfresco treatments at The Retreat, and experience unforgettable dining at venues like The Glass House? With so many venues, there’s something for everyone onboard Azura.

  • Mega Ship
  • British
  • Family-Friendly

Cruise: Valletta – Korčula – Zadar – Trieste – Split – Valletta